Effect of corticosteroids on lymphocyte activation
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چکیده
منابع مشابه
Effect of corticosteroids on lymphocyte activation.
Human peripheral blood lymphocytes were stimulated by concanavalin A, sodium periodate, and neuraminidase plus galactose oxidase. Response to mitogens was measured by the amount of tritiated thymidine incorporated as well as the percent of "giant sheep red blood cell rosettes" generated. The thymidine incorporation was diminished by the absence of monocytes or the presence of corticosteroids. T...
متن کاملHuman lymphocyte subpopulations. Effect of corticosteroids.
Normal subjects given 60 mg of prednisone orally at 8:00 a.m. developed a transient lymphopenia at 2:00 p.m. To define the populations of lymphocytes affected the number and type of lymphocytes in the peripheral blood were assayed. "Late" and "early" spontaneous sheep red blood cell rosettes were used as markers for thymus-derived (T) lymphocytes and one of its subpopulations, respectively. Rec...
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15 صفحه اولEffect of sodium butyrate on lymphocyte activation
Butyrate, in relatively low concentrations, has been shown to induce synthesis of enzymes, cause changes in cell morphology, and inhibit growth of a variety of mammalian cells in tissue culture (reviewed in [1]). In this communication, we report our observations on the effect of butyrate on lymphocyte activation. Butyrate completely and reversibly inhibits mitogen-induced blast formation. We pr...
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ژورنال
عنوان ژورنال: Blood
سال: 1977
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v49.6.873.bloodjournal496873